We have a subfamily of pathways that is active during the fetal period called Sonic Hedgehog. If there are mutations in it, it can cause babies to be born as cyclopses. This is common in mt goats & sheep in the west because there is a plant Veratrum californicum/Corn Lily/Cow Cabbage that if eaten around the 14th day gestation and it causes the mutation in the Sonic Hedgehog pathway & the babies can be born as cyclops. And yes, it's named after the game, Sonic the Hedgehog.
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